Vaccines are undoubtedly controversial in some circles. With that said, Jim O’Neill, former principal associate deputy secretary at the U.S. Department of Health and Human Services and global health care advisor to Rational Vaccines, suggests the JYNNEOS is safe.
“Much of the anxiety around some of the COVID-19 vaccines stems from the novelty of the mRNA vaccine technology,” he says. “The FDA-approved vaccine that’s being used to prevent monkeypox, JYNNEOS, however, is a live attenuated vaccine, which is a much older vaccine technology that offers broader protection and has decades of safety data as compared to subunit vaccines. This technology has been used in successful vaccines for measles, mumps, rubella and tuberculosis, and it eliminated smallpox.”
A second vaccine for smallpox called ACAM2000 is also being administered for monkeypox on an “expanded access” basis, but delivery is more complicated, and it can have adverse side effects.
The consensus seems to be that JYNNEOS, in particular, is safe, and the biggest challenge in getting it to high-risk populations is supply. It’s given in two doses four weeks apart, and efforts are ramping up to increase the number of available doses.
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